Hauner H
Else-Kröner-Fresenius-Zentrum für Ernährungsmedizin, Klinikum Rechts der Isar der TU München.
Chirurg. 2005 Jul;76(7):647-52. doi: 10.1007/s00104-005-1055-5.
Obesity, defined as a body mass index of > or =30 kg/m(2), is a modern epidemic and is increasing worldwide. Depending on genetic make-up, lifestyle factors such as nutrition, physical activity, and psychosocial conditions are the main determinants of its manifestation and severity. Numerous epidemiological studies show consistently that obesity is associated with many comorbidities and, moreover, reduces life expectancy. For this reason, there is a need for evidence-based treatment considering the individual risk. For patients with extreme obesity exceeding a BMI of 40 kg/m(2), surgical intervention is the most effective treatment, not only to improve most somatic and psychological comorbidities significantly but also to prolong life.
肥胖定义为体重指数大于或等于30kg/m²，是一种现代流行病，且在全球范围内呈上升趋势。根据基因构成，营养、体育活动和心理社会状况等生活方式因素是其表现和严重程度的主要决定因素。大量流行病学研究一致表明，肥胖与许多合并症相关，而且会缩短预期寿命。因此，需要根据个体风险进行循证治疗。对于体重指数超过40kg/m²的极度肥胖患者，手术干预是最有效的治疗方法，不仅能显著改善大多数躯体和心理合并症，还能延长寿命。
