Oemus K, Gerlach H, Rath F W
Institut für Pathologische Anatomie Martin-Luther-Universität Halle-Wittenberg.
Zentralbl Neurochir. 1992;53(1):25-32.
Shunting of cerebrospinal fluid to extracranial spaces has been a common and effective procedure for symptomatic therapy of hydrocephalus since the fifties. In 1954 the first spreading of tumor cells via a ventriculo-pleural shunt was reported. We are presenting a case of a 10 month old girl with a medulloblastoma of the lower brain stem with spreading of the intracranial tumor through a ventriculoperitoneal shunt. Further 43 cases of the world literature with shunt-associated metastasizing of brain tumors are analysed. The extraneural spreading of tumor cells through shunt tubes must be considered as a possible complication of the shunting procedure.
自20世纪50年代以来,将脑脊液分流至颅外间隙一直是治疗脑积水症状的常见且有效的方法。1954年,首次报道了肿瘤细胞通过脑室-胸膜分流扩散的情况。我们报告了一例10个月大的女孩,患有脑干下部髓母细胞瘤,颅内肿瘤通过脑室-腹腔分流扩散。此外,还分析了世界文献中另外43例与分流相关的脑肿瘤转移病例。肿瘤细胞通过分流管在神经外扩散必须被视为分流手术可能的并发症。