Dean B L, Lee C, Kirsch J E, Runge V M, Dempsey R M, Pettigrew L C
Barrow Neurological Institute, St. Joseph Hospital and Medical Center, Phoenix, AZ 85013.
AJNR Am J Neuroradiol. 1992 Jan-Feb;13(1):39-48.
To assess the degree and regional pattern of first-pass brain enhancement using dynamic MR imaging.
Ultrafast MR imaging (1.06-second acquisition time per image) was performed in 19 healthy subjects following a bolus IV injection of a gadolinium contrast agent; 36 patients with suspected pathology were studied using the same protocol.
Calculated percent blood volumes were 4.9% for right cortical gray matter, 4.8% for left cortical gray matter, and 2.6% for white matter. Subtraction images were obtained that depicted the first pass "blood pool" pattern of enhancement (gray and white matter) which was significant.
Preliminary evidence suggests utility for cerebral "blood pool" imaging, especially if reduced image acquisition times can be achieved.
使用动态磁共振成像评估首次通过时脑强化的程度和区域模式。
对19名健康受试者静脉注射钆对比剂团注后进行超快磁共振成像（每张图像采集时间为1.06秒）；对36名疑似病变患者采用相同方案进行研究。
计算得出右侧皮质灰质血容量百分比为4.9%，左侧皮质灰质为4.8%，白质为2.6%。获得了描绘首次通过时强化的“血池”模式（灰质和白质）的减影图像，这种强化很显著。
初步证据表明脑“血池”成像有实用价值，尤其是如果能缩短图像采集时间的话。
