脑血流动力学与脑血容量：使用钆对比剂和T1加权快速扰相梯度回波成像的磁共振评估
Cerebral hemodynamics and cerebral blood volume: MR assessment using gadolinium contrast agents and T1-weighted Turbo-FLASH imaging.
作者信息
Dean B L, Lee C, Kirsch J E, Runge V M, Dempsey R M, Pettigrew L C
机构信息
Barrow Neurological Institute, St. Joseph Hospital and Medical Center, Phoenix, AZ 85013.
出版信息
AJNR Am J Neuroradiol. 1992 Jan-Feb;13(1):39-48.
Abstract
PURPOSE
To assess the degree and regional pattern of first-pass brain enhancement using dynamic MR imaging.
MATERIALS AND METHODS
Ultrafast MR imaging (1.06-second acquisition time per image) was performed in 19 healthy subjects following a bolus IV injection of a gadolinium contrast agent; 36 patients with suspected pathology were studied using the same protocol.
RESULTS
Calculated percent blood volumes were 4.9% for right cortical gray matter, 4.8% for left cortical gray matter, and 2.6% for white matter. Subtraction images were obtained that depicted the first pass "blood pool" pattern of enhancement (gray and white matter) which was significant.
CONCLUSION
Preliminary evidence suggests utility for cerebral "blood pool" imaging, especially if reduced image acquisition times can be achieved.
摘要
目的
使用动态磁共振成像评估首次通过时脑强化的程度和区域模式。
材料与方法
对19名健康受试者静脉注射钆对比剂团注后进行超快磁共振成像（每张图像采集时间为1.06秒）；对36名疑似病变患者采用相同方案进行研究。
结果
计算得出右侧皮质灰质血容量百分比为4.9%，左侧皮质灰质为4.8%，白质为2.6%。获得了描绘首次通过时强化的“血池”模式（灰质和白质）的减影图像，这种强化很显著。
结论
初步证据表明脑“血池”成像有实用价值，尤其是如果能缩短图像采集时间的话。
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