Kalra Harish, Tandon Rajul, Trivedi Jitendra Kumar, Janca Aleksandar
Department of Psychiatry, Royal Perth Hospital, Perth WA 6000, Australia.
Ann Gen Psychiatry. 2005 Jun 15;4(1):12. doi: 10.1186/1744-859X-4-12.
Pregnancy is a well-recognised risk factor in precipitating obsessive-compulsive disorder. We present and discuss a case with the onset of obsessive-compulsive disorder in the fourth month of gestation, which fully recovered two weeks after delivery. The phenomenology of the observed disorder was similar to earlier reports of obsessive-compulsive disorder in pregnancy, i.e. the obsessions and compulsions were predominantly related to the concern of contaminating the foetus resulting in washing compulsions. Despite the initial success with anti-obsessional drugs, the patient stopped the medication in the last month of gestation. Nevertheless, she fully recovered two weeks after the delivery without any psychiatric intervention. There were no obsessive-compulsive symptoms at one-year follow up. The possible mechanisms involved in the aetiology of this case, and future research directions in understanding the role of pregnancy in OCD are discussed.
怀孕是引发强迫症的一个公认风险因素。我们呈现并讨论一例在妊娠第四个月发病的强迫症病例,该患者在产后两周完全康复。所观察到的这种疾病的现象学与先前关于孕期强迫症的报道相似,即强迫观念和强迫行为主要与担心污染胎儿从而导致洗涤强迫行为有关。尽管抗强迫药物最初取得了成功,但患者在妊娠最后一个月停止了用药。然而,她在产后两周未经任何精神科干预就完全康复了。在一年的随访中没有出现强迫症状。本文讨论了该病例病因学中可能涉及的机制,以及未来在理解妊娠在强迫症中的作用方面的研究方向。