Tarwotjo I, Katz J, West K P, Tielsch J M, Sommer A
Indonesian Nutritional Blindness Prevention Project, Bandung.
Am J Clin Nutr. 1992 Jun;55(6):1142-6. doi: 10.1093/ajcn/55.6.1142.
Approximately 4000 preschool children in West Java, Indonesia, were examined for xerophthalmia and weighed and measured at 3-mo intervals from March 1977 to December 1978. Children recovering from xerophthalmia over a 3-mo interval gained an average of 124 g (95% CI 42-206) more over 3 mo than normal children. Their height gain was similar to normal children's. Children who developed xerophthalmia during a 3-mo period gained 199 g (95% CI 114-313) less and grew 0.28 cm (95% CI 0.12, 0.44) less than their normal peers. Children with chronic xerophthalmia gained 120 g (95% CI 49-191) less and grew 0.21 cm (95% CI 0.05-0.37) less than normal children. These data suggest that linear and ponderal growth is adversely affected by chronic and incident xerophthalmia, but that catch-up ponderal growth is experienced by children recovering from xerophthalmia.
1977年3月至1978年12月期间,对印度尼西亚西爪哇省约4000名学龄前儿童进行了干眼症检查,并每隔3个月测量一次体重和身高。在3个月的时间里,从干眼症中恢复的儿童在3个月内平均比正常儿童多增重124克(95%置信区间42 - 206)。他们的身高增长与正常儿童相似。在3个月内患上干眼症的儿童比正常同龄人少增重199克(95%置信区间114 - 313),少长高0.28厘米(95%置信区间0.12, 0.44)。患有慢性干眼症的儿童比正常儿童少增重120克(95%置信区间49 - 191),少长高0.21厘米(95%置信区间0.05 - 0.37)。这些数据表明,慢性和突发性干眼症会对线性生长和体重增长产生不利影响,但从干眼症中恢复的儿童会出现体重追赶性增长。