Greco Andres J, Baluarte Jorge H, Meyers Kevin E C, Sellers Marty T, Suchi Mariko, Biegel Jaclyn A, Kaplan Bernard S
Department of Surgery, The Children's Hospital of Philadelphia, PA 19104, USA.
Am J Kidney Dis. 2005 Jun;45(6):e105-8. doi: 10.1053/j.ajkd.2005.03.012.
Renal cell carcinoma can occur in children who have received renal allografts from adults. Chromophobe renal cell carcinoma is a rare variant of renal carcinoma with distinct histochemical, ultrastructural, and genetic characteristics. We describe the incidental finding of a chromophobe renal cell carcinoma in a 13 1/2-year-old boy 5 years after receiving a living-related renal transplant. This tumor was found by serendipity during the evaluation of fever and inguinal lymphadenopathy, with the presumptive diagnosis of posttransplantation lymphoproliferative disorder. The patient was found to have cat-scratch disease. A renal cell carcinoma should be considered in the differential diagnosis of a pediatric recipient of an adult kidney with an incidental finding of a tumor in the graft.
肾细胞癌可发生于接受成人肾移植的儿童。嫌色性肾细胞癌是一种罕见的肾癌变异型，具有独特的组织化学、超微结构和遗传学特征。我们描述了一名13岁半男孩在接受亲属活体肾移植5年后偶然发现嫌色性肾细胞癌的情况。该肿瘤是在评估发热和腹股沟淋巴结病时偶然发现的，初步诊断为移植后淋巴细胞增生性疾病。结果发现该患者患有猫抓病。对于接受成人肾脏移植的儿童，在移植肾中偶然发现肿瘤时，鉴别诊断应考虑肾细胞癌。
