Seven Huseyin, Coskun Berna Uslu, Calis Asli B, Sayin Ibrahim, Turgut Suat
Department of Otolaryngology, Sisli Etfal Training and Research Hospital, Istanbul, Turkey.
Eur Arch Otorhinolaryngol. 2005 Oct;262(10):847-51. doi: 10.1007/s00405-004-0903-0. Epub 2005 Jun 15.
Intracranial abscesses are serious complications of chronic suppurative otitis media (COM). This study included 32 patients presenting with intracranial abscesses from 780 patients hospitalized for treatment of COM. The 32 patients had 59 intracranial complications. Perisinus abscess (13 of 32) was the most common intracranial abscess, followed by temporal lobe abscess (8 of 32), epidural abscess (7 of 32), cerebellar abscess (6 of 32) and subdural empyema (2 of 32). Headache (93%), fever (87%) and altered mental status (62%) were the most common presenting symptoms and signs, along with symptoms of COM. All patients were treated with intravenous antibiotics and canal wall down mastoidectomy. Cholesteatoma with granulation tissue and bony defects at the sinus plate and/or dural plate were seen in most of the patients. Gram negative bacilli and anaerobes were the most common organisms cultured from the abscesses. Three patients had neurological sequels. One patient died. The early diagnosis of these complications requires a high index of suspicion and imaging studies. A multidisciplinary and coordinated approach is important for the management of these patients.
颅内脓肿是慢性化脓性中耳炎(COM)的严重并发症。本研究纳入了780例因COM住院治疗的患者中32例出现颅内脓肿的患者。这32例患者共有59例颅内并发症。窦周脓肿(32例中的13例)是最常见的颅内脓肿,其次是颞叶脓肿(32例中的8例)、硬膜外脓肿(32例中的7例)、小脑脓肿(32例中的6例)和硬膜下积脓(32例中的2例)。头痛(93%)、发热(87%)和精神状态改变(62%)是最常见的症状和体征,同时伴有COM的症状。所有患者均接受静脉抗生素治疗及开放式乳突根治术。大多数患者可见胆脂瘤伴肉芽组织以及窦板和/或硬膜板骨质缺损。革兰氏阴性杆菌和厌氧菌是从脓肿中培养出的最常见病原体。3例患者有神经后遗症。1例患者死亡。这些并发症的早期诊断需要高度的怀疑指数和影像学检查。多学科协作的方法对这些患者的管理很重要。