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在泰国,志贺氏菌病仍是5岁以下儿童面临的一个重要问题。

Shigellosis remains an important problem in children less than 5 years of age in Thailand.

作者信息

Lee H, Kotloff K, Chukaserm P, Samosornsuk S, Chompook P, Deen J L, Von Seidlein L, Clemens J D, Wanpen C

机构信息

International Vaccine Institute, Research Park, San 4-8 Bongcheon-7-Dong, Kwanak-gu, Seoul, South Korea.

出版信息

Epidemiol Infect. 2005 Jun;133(3):469-74. doi: 10.1017/s0950268804003590.

Abstract

This is a review of existing data on the burden of shigellosis in Thailand to determine trends, vulnerable groups, predominant species and serotypes, and antimicrobial resistance patterns. Diarrhoea and dysentery morbidity and mortality data from 1991 to 1999 was collected from the routine surveillance system and demographic data from the government census. International and local literature published between 1988 and 2000 was systematically reviewed. Based on the routine surveillance system, the annual incidence of bacillary dysentery decreased from 1.3 to 0.2/10,000 persons per year. The remaining burden is highest in children <5 years of age at 2.7/10,000 persons per year. In comparison, a prospective study utilizing active surveillance found an incidence in children <5 years of age that was more than 100-fold higher at 640/10,000 persons per year. Despite the decrease in morbidity and mortality based on routinely collected data, shigellosis remains an important problem in children <5 years of age in Thailand.

摘要

这是一篇关于泰国志贺菌病负担的现有数据综述,以确定其趋势、弱势群体、主要菌种和血清型以及抗菌药物耐药模式。1991年至1999年的腹泻和痢疾发病率及死亡率数据来自常规监测系统,人口数据来自政府人口普查。对1988年至2000年间发表的国际和国内文献进行了系统综述。基于常规监测系统,细菌性痢疾的年发病率从每年1.3/10000人降至0.2/10000人。其余负担在5岁以下儿童中最高,为每年2.7/10000人。相比之下,一项采用主动监测的前瞻性研究发现,5岁以下儿童的发病率高出100多倍,为每年640/10000人。尽管根据常规收集的数据发病率和死亡率有所下降,但志贺菌病在泰国5岁以下儿童中仍然是一个重要问题。

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