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外周动脉疾病患者腹主动脉瘤的检测。

Detection of abdominal aortic aneurysm in patients with peripheral artery disease.

作者信息

Barba A, Estallo L, Rodríguez L, Baquer M, Vega de Céniga M

机构信息

Department of Angiology and Vascular Surgery, Hospital de Galdakao, Bizkaia, Spain.

出版信息

Eur J Vasc Endovasc Surg. 2005 Nov;30(5):504-8. doi: 10.1016/j.ejvs.2005.05.011. Epub 2005 Jun 15.

Abstract

OBJECTIVE

To describe the prevalence of abdominal aortic aneurysms (AAA) in patients with peripheral artery disease (PAD).

DESIGN

Observational, descriptive, transverse study.

PATIENTS AND METHODS

We performed an abdominal ultrasound in 1190 consecutive patients with lower limb chronic ischemia (1/99-12/04). We registered cardiovascular risk factors and clinical data for analysis.

RESULTS

The ultrasound was inconclusive in 24 (2%) patients; 1166 patients completed the study. They were mostly male (93.7%), with an age mean of 67+/-9.9 years (37.7-93.4). The main cardiovascular risk factors were: smoking (80.9%), hypertension (41.7%) and hypercholesterolemia (31.4%). The prevalence of AAA was 13% (n = 151). Only 1.5% (n = 17) of the patients had a large AAA (>5 cm). The AAA was clearly more prevalent in men (n = 148; 13.6%) than in women (n = 3; 4.1%) (RR 3.47; 95% CI 1.11-10.89; p = 0.02). The prevalence significantly increased with age, with a maximum of 17.1% in over 75-year-old men (p = 0.006). Patients with tibial disease had a significantly higher prevalence of AAA than aortoiliac or femoro-popliteal disease (p = 0.02).

CONCLUSIONS

The prevalence of AAA in patients with PAD is much higher than that reported in the general population. We recommend that an abdominal ultrasound be routinely included in the study of these patients. Over 75-year-old men are at particularly high-risk.

摘要

目的

描述外周动脉疾病(PAD)患者腹主动脉瘤(AAA)的患病率。

设计

观察性、描述性横断面研究。

患者与方法

我们对1190例连续性下肢慢性缺血患者(1999年1月至2004年12月)进行了腹部超声检查。我们记录了心血管危险因素和临床数据以进行分析。

结果

24例(2%)患者的超声检查结果不明确;1166例患者完成了研究。他们大多为男性(93.7%),平均年龄为67±9.9岁(37.7 - 93.4岁)。主要的心血管危险因素为:吸烟(80.9%)、高血压(41.7%)和高胆固醇血症(31.4%)。AAA的患病率为13%(n = 151)。仅1.5%(n = 17)的患者患有大的AAA(>5 cm)。AAA在男性(n = 148;13.6%)中比在女性(n = 3;4.1%)中明显更常见(相对危险度3.47;95%可信区间1.11 - 10.89;p = 0.02)。患病率随年龄显著增加,75岁以上男性中患病率最高达17.1%(p = 0.006)。胫部疾病患者的AAA患病率显著高于主-髂动脉或股-腘动脉疾病患者(p = 0.02)。

结论

PAD患者中AAA的患病率远高于一般人群中报道的患病率。我们建议在对这些患者的研究中常规进行腹部超声检查。75岁以上男性风险尤其高。

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