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多发性外阴巨大纤维上皮性息肉:1例罕见病例

Multiple Vulvar Giant Fibroepithelial Polyps: A Rare Case Occurrence.

作者信息

Kurniadi Andi, Rinaldi Andi, Yulianti Herry, Bazar Abi Ryamafi, Prasetyawati Rose Dita, Tjandraprawira Kevin Dominique

机构信息

Department of Obstetrics and Gynecology, Division of Oncology Gynecology, Padjadjaran University, Bandung, Indonesia.

Department of Obstetrics and Gynecology, Division of Urogynecology and Reconstructive Surgery, Padjadjaran University, Bandung, Indonesia.

出版信息

Case Rep Obstet Gynecol. 2022 Mar 29;2022:5712925. doi: 10.1155/2022/5712925. eCollection 2022.

DOI:10.1155/2022/5712925
PMID:35392425
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8983256/
Abstract

Fibroepithelial polyps or acrochordons are benign skin tumors of mesenchymal and ectodermal origin. They are seen in 25% of the population, and their frequency increases with age. They are often found in areas with skin folds, such as the neck, axilla, submandibular, or inguinal region. However, they can also be located in the genital tract. Hormone imbalances may facilitate the development of fibroepithelial polyp s (e.g., high levels of estrogen and progesterone during pregnancy). Larger lesions are likely to arise from the proliferation of mesenchymal cells within the hormonally sensitive subepithelial stromal layer of the lower. Generally, their size does not exceed 5 millimeters. We present a 28-year-old patient with multiple giant fibroepithelial polyps with size of 20 × 12 × 8 cm and 9 × 4 × 2 cm, located on both sides of her vulva. Herein, we presented our patient along with the review of current literature pertaining to the diagnosis and the treatment of fibroepithelial polyps (FEPs) and the factors leading to excessive growth.

摘要

纤维上皮性息肉或皮赘是一种起源于间充质和外胚层的良性皮肤肿瘤。人群中25%的人会出现这种肿瘤,其发病率随年龄增长而增加。它们常出现在皮肤褶皱处,如颈部、腋窝、下颌下或腹股沟区。然而,它们也可能位于生殖道。激素失衡可能会促使纤维上皮性息肉的形成(例如,怀孕期间雌激素和孕激素水平升高)。较大的病变可能源于下部激素敏感的上皮下间质层中间充质细胞的增殖。一般来说,它们的大小不超过5毫米。我们报告了一名28岁的患者,其双侧外阴有多个巨大的纤维上皮性息肉,大小分别为20×12×8厘米和9×4×2厘米。在此,我们介绍了我们的患者,并回顾了有关纤维上皮性息肉(FEPs)的诊断、治疗以及导致过度生长的因素的当前文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b613/8983256/7aace5058fad/CRIOG2022-5712925.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b613/8983256/f4a1501fb507/CRIOG2022-5712925.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b613/8983256/995d7d963c1e/CRIOG2022-5712925.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b613/8983256/100700ee2c7f/CRIOG2022-5712925.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b613/8983256/7aace5058fad/CRIOG2022-5712925.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b613/8983256/f4a1501fb507/CRIOG2022-5712925.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b613/8983256/995d7d963c1e/CRIOG2022-5712925.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b613/8983256/100700ee2c7f/CRIOG2022-5712925.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b613/8983256/7aace5058fad/CRIOG2022-5712925.004.jpg

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本文引用的文献

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Am J Case Rep. 2022 Jan 16;23:e933198. doi: 10.12659/AJCR.933198.
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An Unusual Presentation of Giant Fibroepithelial Polyp of the Vagina.阴道巨大纤维上皮性息肉的一种不寻常表现
Iran J Pathol. 2021 Fall;16(4):456-460. doi: 10.30699/IJP.2021.522689.2566. Epub 2021 Jun 6.
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Giant Fibroepithelial Polyps: Why do they Grow Excessively?巨大纤维上皮性息肉:为何它们会过度生长?
外阴溃疡性纤维上皮性间质息肉,高度怀疑外阴恶性肿瘤:一例病例报告及文献综述
Med Int (Lond). 2025 Apr 1;5(3):31. doi: 10.3892/mi.2025.230. eCollection 2025 May-Jun.
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An Expanding Large Acrochordon on the Labia Majora Requiring Surgical Intervention.一例需要手术干预的大阴唇巨大皮赘不断增大
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A case of multiple soft fibromas complicated with pityriasis versicolor during pregnancy: A case report.一例孕期多发性软纤维瘤合并花斑糠疹:病例报告
SAGE Open Med Case Rep. 2024 Aug 16;12:2050313X241274891. doi: 10.1177/2050313X241274891. eCollection 2024.
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