麦角酸二乙胺治疗期间的精神副作用。

Psychiatric side effects during methysergide treatment.

作者信息

Cittadini E, Goadsby P J

机构信息

Institute of Neurology and the National Hospital for Neurology and Neurosurgery, London, UK.

出版信息

J Neurol Neurosurg Psychiatry. 2005 Jul;76(7):1037-8. doi: 10.1136/jnnp.2004.048363.

DOI:10.1136/jnnp.2004.048363

PMID:15965225

Abstract

A patient is reported with psychological change characterised by impaired concentration and thought projection, followed by both severe anxiety and depression, starting after three weeks on high dose methysergide. The acute problem settled slowly after methysergide withdrawal and is likely to represent an unusual and serious side effect of that drug.

摘要

据报道，一名患者出现心理变化，其特征为注意力不集中和思维投射受损，继之出现严重焦虑和抑郁，这些症状在高剂量服用麦角新碱三周后开始出现。停用麦角新碱后，急性问题逐渐缓解，这可能是该药物一种罕见且严重的副作用。