Sakai Mitsuru, Nakao Akimasa, Kaneko Tetsuya, Takeda Shin, Inoue Soichiro, Yagi Yoshikazu, Okochi Osamu, Ota Toyohiro, Ito Shigeki
Departments of Surgery II, Nagoya University School of Medicine Nagoya, Japan.
Hepatogastroenterology. 2005 May-Jun;52(63):749-52.
A 54-year-old woman, who had undergone pancreatoduodenectomy with resection of the portal vein and intraoperative radiation therapy for cancer of the lower bile duct 16 months before, visited our institution complaining of melena. To identify the cause of bleeding and severe anemia, we performed gastrointestinal endoscopy but could detect no obvious source. The portal phase of the superior mesenteric arteriography and percutaneous transhepatic portography revealed severe stenosis of the extrahepatic portal vein, which corresponded to the end-to-end anastomosis of the portal vein, and hepatofugal collaterals. Extravasations into the afferent loop of the jejunum were detected only with portography. These findings suggested that portal hypertension due to extrahepatic portal obstruction led to bleeding varices. Subsequent to percutaneous transhepatic portography, we dilated the stenosis of the extrahepatic portal vein using a balloon catheter and placed an expandable metallic stent there. Portography after the treatment revealed the disappearance of the hepatofugal flow to collaterals and extravasations, and the patient has had no further episodes of gastrointestinal bleeding since. In conclusion, for patients with bleeding varices due to extrahepatic portal obstruction, especially after abdominal surgery, percutaneous transhepatic angioplasty is considered to be the treatment of choice because of its efficiency and minimal invasiveness.
一名54岁女性,16个月前因低位胆管癌接受了胰十二指肠切除术,术中切除门静脉并进行了术中放射治疗,现因黑便前来我院就诊。为明确出血及严重贫血的原因,我们进行了胃肠内镜检查,但未发现明显出血源。肠系膜上动脉造影门静脉期及经皮肝门静脉造影显示肝外门静脉严重狭窄,狭窄部位对应门静脉端端吻合处,且存在肝外分流。仅在门静脉造影时发现造影剂外渗至空肠输入袢。这些发现提示肝外门静脉阻塞导致的门静脉高压引起了曲张静脉出血。经皮肝门静脉造影后,我们使用球囊导管扩张了肝外门静脉狭窄处,并置入了可扩张金属支架。治疗后的门静脉造影显示向侧支分流的肝外分流及造影剂外渗消失,此后患者未再发生胃肠道出血。总之,对于肝外门静脉阻塞导致曲张静脉出血的患者,尤其是腹部手术后的患者,经皮肝血管成形术因其有效性和微创性被认为是首选治疗方法。