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经皮经肝门静脉支架置入术治疗肝内胆管癌局部复发所致门静脉高压症

[Percutaneous transhepatic portal vein stenting for portal hypertension caused by local recurrence of intrahepatic cholangiocarcinoma].

作者信息

Kamiya Junichiro, Kato Atsushi, Kimura Fumio, Shimizu Hiroaki, Yoshitome Hiroyuki, Otsuka Masayuki, Furukawa Katsunori, Yoshitomi Hideyuki, Takeuchi Dan, Takayashiki Tsukasa, Suda Kosuke, Takano Shigetsugu, Kuboki Satoshi, Miyazaki Masaru

机构信息

Dept. of General Surgery, Graduate School of Medicine, Chiba University.

出版信息

Gan To Kagaku Ryoho. 2010 Nov;37(12):2726-8.

Abstract

A 62-year-old woman underwent an extended left hepatectomy with a combined resection of portal vein and extrahepatic bile duct for intrahepatic cholangiocarcinoma (ICC). After 7 years, she presented with repeated tarry black stool and severe anemia. The source of bleeding was not identified on upper and lower gastrointestinal endoscopy. Computed tomography (CT) revealed a small hypodence lesion at portal hepatis, by which portal vein (PV) stenosis was induced in the absence of sufficient development of portal venous collateral. Positron emission tomography revealed an accumulation of fluorodeoxy glucose around PV obstruction. Based on these findings, we diagnosed that the local recurrence of ICC, which resulted in mesenteric hypertension and small bowel varices. Therefore, portal stent placement was carried out under percutaneous transhepatic portgraphy to maintain portal blood flow. An uncovered expandable metallic stent was inserted into the stenotic region. Portgraphy after the stent replacement showed a relief of the PV stenosis and disappearance of the collateral pathways. After this procedure, the patient had no additional episode of gastrointestinal hemorrhage. Our experience suggests that stent placement for postoperative PV stenosis is recommended as a useful treatment for gastrointestinal bleeding caused by portal hypertension that is less invasive.

摘要

一名62岁女性因肝内胆管癌(ICC)接受了扩大左肝切除术,联合门静脉和肝外胆管切除术。7年后,她出现反复黑便和严重贫血。上、下消化道内镜检查未发现出血源。计算机断层扫描(CT)显示肝门部有一个小的低密度病变,由于门静脉(PV)侧支循环未充分发育,导致门静脉狭窄。正电子发射断层扫描显示氟脱氧葡萄糖在门静脉梗阻周围积聚。基于这些发现,我们诊断为ICC局部复发,导致肠系膜高压和小肠静脉曲张。因此,在经皮肝穿刺门静脉造影术下行门静脉支架置入术以维持门静脉血流。将一个裸金属可扩张支架插入狭窄区域。支架置入术后的门静脉造影显示门静脉狭窄缓解,侧支循环消失。此手术后,患者未再发生胃肠道出血。我们的经验表明,对于术后门静脉狭窄进行支架置入术,作为一种侵入性较小的治疗门静脉高压引起的胃肠道出血的方法是值得推荐的。

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