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[帕金森病及相关疾病]

[Parkinson's disease and associated disorders].

作者信息

Tison François, Ghorayeb Imad

机构信息

Service de neurologie, hôpital du Haut-Lévêque, 33604 Pessac Cedex.

出版信息

Rev Prat. 2005 Apr 15;55(7):741-7.

Abstract

Besides the core motor features of Parkinson's disease, other disorders such as gastro-intestinal dysfunction, postural hypotension, urinary, genital, sleep problems and pain contribute to the alteration of patient's quality of life. Drooling, swallowing difficulties and constipation are the more frequent digestive problems. Aspirations may be life-threatening. Sexual dysfunction as well as iatrogenic hypersexuality may be deleterious for the couple well-being. Symptomatic postural hypotension is the main manifestation of autonomic failure and needs a specific management. Pain is frequent in Parkinson's disease, particularly due to frozen shoulder or to the peculiar picture of "primary sensory pain symptoms". Sleep disorders are common in Parkinson's disease and are associated with reduced quality of life and increased risk of vehicle accident particularly when excessive daytime somnolence occurs.

摘要

除帕金森病的核心运动特征外,其他病症如胃肠功能障碍、体位性低血压、泌尿、生殖、睡眠问题和疼痛等,都会导致患者生活质量的改变。流口水、吞咽困难和便秘是较常见的消化问题。误吸可能危及生命。性功能障碍以及医源性性欲亢进可能对夫妻关系产生有害影响。症状性体位性低血压是自主神经功能衰竭的主要表现,需要特殊处理。疼痛在帕金森病中很常见,尤其是由于肩周炎或“原发性感觉性疼痛症状”的特殊表现所致。睡眠障碍在帕金森病中很常见,与生活质量下降和交通事故风险增加有关,特别是当出现白天过度嗜睡时。

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