Abdelgabar A, Sharma J
Department of Elderly Medicine, Princess of Wales Hospital, Grimsby, UK.
Int J Clin Pract. 2003 Nov;57(9):781-7.
Sleep quality is one of the major sources of dissatisfaction among patients with Parkinson's disease (PD). Insomnia, parasomnia and daytime sleep disorders are all common. The motor problems accompanying PD are well studied and documented, yet little is known about sleep and the other non-motor problems. Dopaminergic medications, the neurochemical and neurodegenerative changes may all contribute to the pathogenesis of sleep disorders in PD. Subjective or objective sleepiness assessment should routinely be performed by physicians looking after PD patients. Patients should be informed of the risks associated with excessive daytime sleepiness. Management is difficult and should be targeted to the specific sleep disorder and its likely cause. Simple sleep measures such as sleep hygiene should be tried first before pharmacological treatment is initiated.
睡眠质量是帕金森病（PD）患者不满的主要来源之一。失眠、异态睡眠和日间睡眠障碍都很常见。伴随PD的运动问题已得到充分研究和记录，但关于睡眠及其他非运动问题却知之甚少。多巴胺能药物、神经化学和神经退行性改变都可能导致PD睡眠障碍的发病机制。照料PD患者的医生应常规进行主观或客观的嗜睡评估。应告知患者与日间过度嗜睡相关的风险。管理困难，应针对特定的睡眠障碍及其可能的病因。在开始药物治疗之前，应首先尝试简单的睡眠措施，如睡眠卫生。
