Skhiri Habib, Guedri Yousr, Achour Abdellatif, Sabra Aloui, Hadj Youssef Dorsaf, Bouraoui Samia, Frih Ameur, Ben Dhia Nasr, Sakkouhi Mohamed, Gahbiche Mourad, Saad Hamadi, El May Mezni
Service de Nephrologie, CHU Fattouma Bourguiba Monastir.
Tunis Med. 2005 Apr;83(4):240-2.
Women with end-stage renal disease or on regular dialysis have low fertility. Renal transplantation restores not only normal renal and endocrine functions but also the reproductive function as well and this conception becomes possible. Pregnancy in transplanted women is at higher risk and necessitates a multidisciplinary follow up. We report the course and out come of two successful pregnancies, the second was the first case of twin pregnancy in Tunisia in a transplanted woman. Our patient is 35 years old had a chronic renal insufficiency, secondary to interstitial nephropathy. After six years of hemodialysis, she had received a renal graft from a living donor (his brother). A double drug immunosuppression was given (Prednisolone - Azathioprine). Two years later, she became pregnant and delivered a normal baby at term, and one year later she had a twin pregnancy that ended successfully and delivered by caesarian section a two babies with different sex. Pregnancy after renal transplantion must be considered as a risk factor for any subsquent pregnancy, and the risk nicreases in case of twin pregnancy.
患有终末期肾病或接受定期透析的女性生育能力较低。肾移植不仅能恢复正常的肾脏和内分泌功能，还能恢复生殖功能，从而使受孕成为可能。移植女性怀孕的风险更高，需要多学科随访。我们报告了两例成功妊娠的过程和结果，第二例是突尼斯首例移植女性双胎妊娠。我们的患者35岁，患有继发于间质性肾病的慢性肾功能不全。经过六年的血液透析后，她接受了来自活体供体（其兄弟）的肾移植。给予了双重药物免疫抑制治疗（泼尼松龙 - 硫唑嘌呤）。两年后，她怀孕并足月产下一名正常婴儿，一年后她怀了双胞胎并成功分娩，通过剖宫产产下了两个不同性别的婴儿。肾移植后的妊娠必须被视为任何后续妊娠的危险因素，双胎妊娠时风险会增加。
