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脊髓型颈椎病:前路减压融合术的10年前瞻性疗效分析

Cervical spondylotic myelopathy: 10 years of prospective outcome analysis of anterior decompression and fusion.

作者信息

Chagas Haroldo, Domingues Flavio, Aversa Antonio, Vidal Fonseca Ana Luiza, de Souza Jorge Marcondes

机构信息

Division of Neurosurgery, University Hospital-Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

出版信息

Surg Neurol. 2005;64 Suppl 1:S1:30-5; discussion S1:35-6. doi: 10.1016/j.surneu.2005.02.016.

DOI:10.1016/j.surneu.2005.02.016
PMID:15967227
Abstract

BACKGROUND

Fifty-one patients with cervical spondylotic myelopathy (CSM) treated by anterior cervical corpectomy with fusion (ACWF) at our institution were included in a study during a period of 10 years to evaluate neurological, anatomical, and functional outcomes including satisfaction levels.

METHODS

We have completed a prospective evaluation of 39 patients with spondylotic myelopathy submitted to ACWF during the period of 1989-2000. The data were analyzed for age, duration of symptoms, severity of preoperative neurological deficit, and single-level or multilevel compressive status looking for possible association with prognostic surrogate data and clinical outcome that were evaluated with the Nurick score and a survey of level of satisfaction.

RESULTS

Of the 51 patients, 39 fullfilled the intended follow-up being 28 men (71.8%) and 11 women (28.2%). The average age was 63.5 years. Duration of symptoms ranged from 1 to 240 months (mean, 38.1 months). The mean preoperative Nurick scale score was 2.97; the mean postoperative score was 2.1. The most frequently involved vertebral body was C5 (71.7%). The follow-up period was longer than 18 months for all patients. Postoperative nonneurological complications occurred in 8 patients (15.6%). The mortality rate was 1.9% (n = 1). Postoperative results showed improvement in 25 patients (64.1%), no change in 13 (33.3%), and worsening in 1 (2.6%). The correlation coefficient of preoperative and postoperative Nurick scores was 0.733 (R(2) = 0.53). Of the 39 patients, 31 answered the questionnaire for quality of life-19 (61.2%) were very satisfied, 6 were satisfied (19.35%), and 6 were not satisfied (19.35%).

CONCLUSION

Most patients (80.6%) were very satisfied or satisfied with the outcome and would decide again for the surgery (87%) if the results were previously known. Anterior cervical corpectomy with fusion was a reliable and rewarding procedure for CSM, with functional improvement in most patients. Excellent long-term outcome results in cervical fusion can be achieved without the use of hardware instrumentation.

摘要

背景

在10年期间,我们机构纳入了51例行颈椎前路椎体次全切除融合术(ACWF)治疗的脊髓型颈椎病(CSM)患者,以评估神经、解剖和功能结局,包括满意度。

方法

我们对1989年至2000年期间接受ACWF治疗的39例脊髓型颈椎病患者进行了前瞻性评估。分析了患者的年龄、症状持续时间、术前神经功能缺损严重程度以及单节段或多节段受压情况,以寻找与预后替代数据和临床结局的可能关联,临床结局通过Nurick评分和满意度调查进行评估。

结果

51例患者中,39例完成了预期随访,其中男性28例(71.8%),女性11例(28.2%)。平均年龄为63.5岁。症状持续时间为1至240个月(平均38.1个月)。术前Nurick量表平均评分为2.97;术后平均评分为2.1。最常受累椎体为C5(71.7%)。所有患者随访期均超过18个月。8例患者(15.6%)发生术后非神经并发症。死亡率为1.9%(n = 1)。术后结果显示好转25例(64.1%),无变化13例(33.3%),恶化1例(2.6%)。术前和术后Nurick评分的相关系数为0.733(R² = 0.53)。39例患者中,31例回答了生活质量问卷,其中61.2%的患者非常满意,6例满意(19.35%),6例不满意(19.35%)。

结论

大多数患者(80.6%)对结局非常满意或满意,并且如果事先知道结果,87%的患者会再次选择该手术。颈椎前路椎体次全切除融合术是治疗CSM的可靠且有益的手术,大多数患者功能得到改善。不使用内固定器械也可实现颈椎融合的优异长期结局。

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