2-硫脲嘧啶在热解石墨电极上的电化学氧化

Electrochemical oxidation of 2-thiouracil at pyrolytic graphite electrode.

作者信息

Goyal Rajendra N, Singh Udai P, Abdullah Adil A

机构信息

Department of Chemistry, Indian Institute of Technology Roorkeem, Roorkee 247 667, India.

出版信息

Bioelectrochemistry. 2005 Sep;67(1):7-13. doi: 10.1016/j.bioelechem.2004.11.001. Epub 2005 Feb 5.

DOI:10.1016/j.bioelechem.2004.11.001

PMID:15967396

Abstract

2-Thiouracil has been studied in phosphate buffers of pH 1.95-11.08 using linear and cyclic sweep voltammetry, coulometry, controlled potential electrolysis and spectral studies. One well-defined oxidation peak I(a) in the pH range 1.95-11.08 was noticed. The number of electrons involved in peak I(a) was found to be four in a thin layer cell whereas under exhaustive electrolysis condition oxidation was found to involve six electrons. A reduction peak II(c) (2e, 2H(+)) is noticed in the reverse sweep. Spectral studies during oxidation were carried out at different pH. Kinetic studies indicated that the decay of the UV-absorbing intermediate is a first order reaction. The products of the electrooxidation have been characterized and a tentative EC mechanism has been suggested for the oxidation of 2-thiouracil.

摘要

使用线性和循环伏安法、库仑法、控制电位电解法和光谱研究法，在pH值为1.95 - 11.08的磷酸盐缓冲液中对2-硫尿嘧啶进行了研究。在pH值1.95 - 11.08范围内观察到一个明确的氧化峰I(a)。在薄层电池中，发现参与峰I(a)的电子数为四个，而在完全电解条件下，氧化过程涉及六个电子。在反向扫描中观察到一个还原峰II(c)（2e，2H(+)）。在不同pH值下进行了氧化过程中的光谱研究。动力学研究表明，紫外线吸收中间体的衰减是一级反应。对电氧化产物进行了表征，并提出了2-硫尿嘧啶氧化的初步EC机制。