Stunkard Albert J, Allison Kelly C, O'Reardon John P
Weight and Eating Disorders Program, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
Appetite. 2005 Oct;45(2):182-6. doi: 10.1016/j.appet.2005.01.013.
The night eating syndrome (NES) is an eating disorder marked by a delay in the circadian pattern of eating that disrupts sleep. Studies have shown that those with NES eat a significant proportion of their calories after their evening meal and wake up during the night to eat. However, the timing of the sleep cycles are phase appropriate, with similar bedtimes and morning wake up times as control subjects, suggesting that the delayed eating rhythm may secondarily disrupt sleep. A case study and an open-label trial with SSRIs suggest that they may treat NES effectively. Randomized controlled trials are needed.
夜间进食综合征(NES)是一种饮食失调症,其特征是昼夜饮食模式延迟,扰乱睡眠。研究表明,患有夜间进食综合征的人在晚餐后摄入的热量占很大比例,并会在夜间醒来进食。然而,睡眠周期的时间是适当的,就寝时间和早晨起床时间与对照组相似,这表明延迟的进食节奏可能会继而扰乱睡眠。一项病例研究和一项使用选择性5-羟色胺再摄取抑制剂(SSRI)的开放标签试验表明,它们可能有效治疗夜间进食综合征。需要进行随机对照试验。