用于水溶液中含硫醇氨基酸和肽的荧光探针。
Fluorescence probes for thiol-containing amino acids and peptides in aqueous solution.
作者信息
Fu Yanyan, Li Hongxiang, Hu Wenping, Zhu Daoben
机构信息
Organic Solid Laboratory, Institute of Chemistry, Chinese Academy of Sciences, Beijing.
出版信息
Chem Commun (Camb). 2005 Jul 7(25):3189-91. doi: 10.1039/b503772g. Epub 2005 May 24.
DOI:10.1039/b503772g
PMID:15968367
Abstract
A new fluorescence probe is described using the "chemosensing ensemble" method. The probe shows high selectivity and sensitivity for thiol-containing amino acids and peptides, and can detect cysteine and homocysteine from healthy to abnormal levels under physiologically-relevant conditions.
摘要
一种采用“化学传感组合”方法的新型荧光探针被报道。该探针对含硫醇的氨基酸和肽表现出高选择性和高灵敏度，并且能够在生理相关条件下检测从健康水平到异常水平的半胱氨酸和高半胱氨酸。
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