Farquharson Stuart, Gift Alan, Maksymiuk Paul, Inscore Frank
Real-Time Analyzers, East Hartford, Connecticut 06108, USA.
Appl Spectrosc. 2005 May;59(5):654-60. doi: 10.1366/0003702053946100.
Detection of chemical agents as poisons in water supplies not only requires microg/L sensitivity, but also requires the ability to distinguish their hydrolysis products. We have been investigating the ability of surface-enhanced Raman spectroscopy (SERS) to detect chemical agents at these concentrations. Here we expand these studies and present the SERS spectra of the nerve agent VX (ethyl S-2-diisopropylamino ethyl methylphosphonothioate) and its hydrolysis products, ethyl S-2-diisopropylamino methylphosphonothioate, 2(diisopropylamino) ethanethiol, ethyl methylphosphonic acid, and methylphosphonic acid. Vibrational mode assignments for the observed SERS peaks are also provided. Overall, each of these chemicals produces a series of peaks between 450 and 900 cm(-1) that are sufficiently unique to allow identification. SERS measurements were performed in silver-doped sol-gel-filled capillaries that are being developed as part of an extractive point sensor.
检测供水中作为毒物的化学制剂不仅需要微克/升的灵敏度，还需要能够区分其水解产物。我们一直在研究表面增强拉曼光谱（SERS）在这些浓度下检测化学制剂的能力。在此，我们扩展这些研究，并展示神经毒剂VX（S-2-二异丙氨基乙基甲基硫代膦酸乙酯）及其水解产物S-2-二异丙氨基甲基硫代膦酸乙酯、2-（二异丙氨基）乙硫醇、乙基甲基膦酸和甲基膦酸的SERS光谱。还提供了观察到的SERS峰的振动模式归属。总体而言，这些化学物质中的每一种都会在450至900厘米-1之间产生一系列足够独特的峰，以便进行识别。SERS测量是在作为萃取点传感器一部分正在开发的掺银溶胶-凝胶填充毛细管中进行的。
