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来自灰绿酸浆的雄甾烷和睡茄内酯

Androstane and withanolides from Physalis cinerascens.

作者信息

Maldonado Emma, Alvarado Vita E, Torres Fernando R, Martínez Mahinda, Pérez-Castorena Ana L

机构信息

Instituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, Coyoacán, México.

出版信息

Planta Med. 2005 Jun;71(6):548-53. doi: 10.1055/s-2005-864157.

DOI:10.1055/s-2005-864157
PMID:15971127
Abstract

Two new withanolides, cinerolide and 24,25-dihydrowithanolide S, together with the new androstane, cinedione, and the known withanolides, visconolide, physalactone, withanolide S and 4beta-hydroxywithanolide E were isolated from the EtOAc extract of leaves, flowers and stems of Physalis cinerascens. The structures of these compounds were established by spectroscopic methods and that of cinerolide was confirmed by X-ray diffraction analysis.

摘要

从灰绿酸浆的叶、花和茎的乙酸乙酯提取物中分离出两种新的维甾烷醇内酯,即灰绿醇内酯和24,25-二氢维甾烷醇内酯S,以及新的雄甾烷类化合物灰绿二酮,还有已知的维甾烷醇内酯、粘果酸内酯、酸浆内酯、维甾烷醇内酯S和4β-羟基维甾烷醇内酯E。这些化合物的结构通过光谱方法确定,灰绿醇内酯的结构通过X射线衍射分析得到证实。

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