Rodallec T, Fiandrino P, Iba-Zizen M-T, Cabanis E, Gastaud P, Nordmann J-P, Baudouin C
CHNO des Quinze-Vingts, 12 rue Bezout, 75014 Paris, France.
J Fr Ophtalmol. 2005 Apr;28(4):401-6. doi: 10.1016/s0181-5512(05)81072-1.
Arteriovenous malformations of the brain (BAVMs) are a relatively rare group involving intracranial vascular lesions (telangiectasia, cavernous malformation, venous anomaly). We report the case of a patient who presented an atypical visual symptomatology revealing a BAVM.
A 48-year-old woman consulted for a recent bilateral visual blur. In darkness, discrete anisocoria appeared on the left eye. At the biomicroscopy light examination, we found areflexic semi-mydriasis (direct and consensual) on the left eye; the light reflex (direct and consensual) on the right eye was normal. During the accommodative reflex test the left pupil contracted. We propose the diagnosis of Adie's pupil, which was confirmed by the pilocarpine test (0.125%). We decided to examine the visual field because the symptomatology of the visual blur remained unexplained. The visual field showed a left homonymous inferior lateral scotoma. MRI showed a right occipital arteriovenous malformation.
A quick examination could confuse painless anisocoria with a compression of the IIIrd intrinsic left nerve. This recent scotoma revealed BAVM progression. The natural history of BAVMs shows that the essential risk of these injuries is the onset of an intracranial hemorrhage. To reach a radical therapeutic decision, a cerebral arteriography clarifying the afferent and efferent vascularity of the nidus was carried out.
This case is original in that it associates the concomitant discovery of a BAVM and Adie's pupil. Symptomatic BAVMs are extremely serious. Planning their treatment requires multidisciplinary cooperation in order to reduce the risk of mortality.
脑动静脉畸形(BAVMs)是一组相对罕见的颅内血管病变(毛细血管扩张症、海绵状血管瘤、静脉畸形)。我们报告了一例出现非典型视觉症状并揭示患有BAVM的患者病例。
一名48岁女性因近期双侧视力模糊前来就诊。在黑暗中,左眼出现轻微不等大瞳孔。在生物显微镜灯光检查时,我们发现左眼有反射消失的半散瞳(直接和间接);右眼的光反射(直接和间接)正常。在调节反射测试中,左侧瞳孔收缩。我们初步诊断为阿狄瞳孔,经毛果芸香碱试验(0.125%)得以证实。由于视力模糊的症状仍无法解释,我们决定检查视野。视野检查显示左侧同向性下外侧暗点。磁共振成像(MRI)显示右侧枕叶动静脉畸形。
快速检查可能会将无痛性不等大瞳孔与左侧动眼神经受压相混淆。近期出现的暗点揭示了BAVM的进展。BAVM的自然病程表明,这些损伤的主要风险是颅内出血的发生。为了做出根治性治疗决策,进行了脑血管造影以明确畸形团的输入和输出血管情况。
该病例的独特之处在于同时发现了BAVM和阿狄瞳孔。有症状的BAVM极其严重。规划其治疗需要多学科合作以降低死亡风险。