Sánchez-Alvarez J C, Altuzarra-Corral A, Mercadé-Cerdá J M, Casado-Chocán J L, Moreno-Alegre V, Rufo-Campos M, Camino-León R, Galán-Barranco J M, Pita-Calandre E, Ramos-Lizana J, Serrano-Castro P J
Servicio de Neurología, Hospital Universitario Virgen de las Nieves, 18013 Granada, España.
Rev Neurol. 2005;40(12):743-50.
The objective of this work was to produce a scientific evidence-based guide to clinical practice dealing with the basic questions concerning the treatment of epilepsy.
A committee of 11 experts belonging to the Andalusia Epilepsy Society, made up of six neurologists, three neuropaediatricians, one neurosurgeon and a pharmacologist, all of whom were deeply involved and experienced in epilepsy, conducted a thorough review of the literature in search of all the evidence available on the proposed subject matter. The following databases were used: MEDLINE, Cochrane Library and the databases of several clinical practice guidelines (National Guideline Clearinghouse, National Institute of Clinical Excellence and the American Academy of Neurology's Clinical Guidelines). The Guide was set out in seven sections and was published in four parts. From a total number of 187 relevant documents, the committee found 63 examples of scientific evidence and 91 therapeutic recommendations. These were tabulated and classified according to the European Federation of Neurological Societies' criteria for producing Clinical Practice Guidelines.
The results of this survey provide scientific evidence-based clinical guidelines that are useful, simple and applicable at different levels of health care.
本研究旨在制定一份基于科学证据的临床实践指南，以应对癫痫治疗的基本问题。
由安达卢西亚癫痫协会的11名专家组成的委员会开展此项工作，该委员会由6名神经科医生、3名神经儿科医生、1名神经外科医生和1名药理学家组成，他们均在癫痫领域有深入参与且经验丰富。委员会对文献进行了全面审查，以查找关于该主题的所有现有证据。使用了以下数据库：MEDLINE、Cochrane图书馆以及若干临床实践指南的数据库（国家指南资料库、国家临床优化研究所和美国神经病学学会临床指南）。该指南分为七个部分，分四部分出版。在总共187份相关文献中，委员会找到了63个科学证据实例和91条治疗建议。这些内容根据欧洲神经科学会联合会制定临床实践指南的标准进行列表和分类。
本次调查结果提供了基于科学证据的临床指南，这些指南实用、简单且适用于不同层次的医疗保健。
