Thevenot Thierry, Vanlemmens Claire, Di Martino Vincent, Becker Marie-Claude, Denue Pierre-Olivier, Kantelip Bernadette, Bresson-Hadni Solange, Heyd Bruno, Mantion Georges, Miguet Jean-Philippe
Hepatology Unit, Hôpital Jean Minjoz, Besançon, France.
Digestive Surgery Unit, Hôpital Jean Minjoz, Besançon, France.
Liver Transpl. 2005 Jul;11(7):834-838. doi: 10.1002/lt.20463.
Liver involvement in hereditary hemorrhagic telangiectasia may lead to high-output cardiac failure. Few data have been reported on orthotopic liver transplantation (OLT) for these patients. In this paper, we describe two patients treated by OLT as a salvage procedure for cardiac failure, and we review literature on this subject. Our two patients resumed normal cardiac function after OLT. This procedure appears to be a promising therapy with good long-term results despite dissection difficulties encountered due to the collateral arterial network reorganization.
遗传性出血性毛细血管扩张症累及肝脏可能导致高输出量心力衰竭。关于这些患者进行原位肝移植(OLT)的报道较少。在本文中,我们描述了两名接受OLT治疗以挽救心力衰竭的患者,并回顾了关于该主题的文献。我们的两名患者在OLT后恢复了正常的心功能。尽管由于侧支动脉网络重组导致解剖困难,但该手术似乎是一种有前景的治疗方法,长期效果良好。