Chen Li, Tao Si-feng, Xu Yuan, Fang Fu, Peng Shu-you
Department of Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
J Zhejiang Univ Sci B. 2005 Jul;6(7):678-81. doi: 10.1631/jzus.2005.B0678.
This study was aimed at evaluating and comparing the quality of life in patients who underwent laparoscopic and open cholecystectomy for chronic cholecystolithiasis.
The study included 25 patients with laparoscopic cholecystectomy (LC group) and 26 with open cholecystectomy (OC group). The quality of life was measured with the Gastrointestinal Quality of Life Index (GLQI) preoperatively, thereafter regularly at 2, 5, 10 and 16 weeks after the operation.
The mean preoperative overall GLQI scores were 112.5 and 110.3 in LC and OC group respectively (P>0.05). In the LC group, the mean overall GLQI score reduced slightly to 110.0 two weeks after the operation (P>0.05). The LC group showed significant improvement in overall score and in the aspects of symptomatology, emotional and physiological status from 5 to 16 weeks postoperatively. In the OC group, the GLQI score reduced to 102.0 two weeks after surgery (P<0.05). Significant reductions were shown in the aspects of symptomatology, physiological and social status. The GLQI scores returned to the preoperative level of 115.6 ten weeks after the operation (P>0.05). The patients experienced significant improvements of GLQI sixteen weeks after OC operation (P<0.01~0.05). Within the 10 postoperative weeks, the LC group had significantly higher GLQI scores than the OC group (P<0.05).
LC can improve the quality of life postoperatively better and more rapidly than OC. The assessment of quality of life assessment is a valid method for measuring the effects of surgical treatment.
本研究旨在评估和比较因慢性胆囊结石接受腹腔镜胆囊切除术和开腹胆囊切除术患者的生活质量。
该研究纳入25例行腹腔镜胆囊切除术的患者(LC组)和26例行开腹胆囊切除术的患者(OC组)。术前使用胃肠道生活质量指数(GLQI)测量生活质量,术后分别于第2、5、10和16周定期测量。
LC组和OC组术前GLQI总评分均值分别为112.5和110.3(P>0.05)。LC组术后2周时,GLQI总评分均值略有下降至110.0(P>0.05)。LC组术后5至16周时,总评分以及症状学、情绪和生理状态方面均有显著改善。OC组术后2周时,GLQI评分降至102.0(P<0.05)。症状学、生理和社会状态方面均有显著下降。术后10周时,GLQI评分恢复至术前水平115.6(P>0.05)。OC组术后16周时患者GLQI有显著改善(P<0.01~0.05)。术后10周内,LC组GLQI评分显著高于OC组(P<0.05)。
与开腹胆囊切除术相比,腹腔镜胆囊切除术能更好且更快地改善术后生活质量。生活质量评估是衡量手术治疗效果的有效方法。