Hussain A, Rahim M A, Azad Khan A K, Ali S M K, Vaaler S
Institute of General Practice and Community Medicine, Department of International Health, University of Oslo, Norway.
Diabet Med. 2005 Jul;22(7):931-6. doi: 10.1111/j.1464-5491.2005.01558.x.
To describe differences in prevalence of Type 2 diabetes mellitus with its associated risk factors between rural and urban populations in Bangladesh. Diagnostic criteria [fasting blood glucose (FBG) and oral glucose tolerance tests (OGTT)] were compared and reviewed for both populations.
A total of 1555 subjects from urban and 4757 from rural communities (age > or = 20 years) with similar cultural and ethnic backgrounds were randomly selected in a cross-sectional survey. FBG values were determined from all and 2-h post-glucose capillary blood samples were determined after a 75-g oral glucose load for a selected number (urban 476, rural 1046).
A higher prevalence of diabetes was found in urban (8.1%) compared with rural populations (2.3%). Age, sex and waist-to-hip ratio for men were significant risk factors for both urban and rural subjects following fasting and 2-h post-glucose values adjusted for a number of confounding variables. Poor agreement was observed between FBG and OGTT for both urban (kappa 0.41) and rural (kappa 0.40) areas.
A higher prevalence of diabetes mellitus (DM) in the urban population was observed compared with rural subjects despite similar body mass indexes (BMI). Differences in obesity, waist/hip ratio or hypertension failed to explain the increasing occurrence of T2DM in the urban population.
描述孟加拉国城乡人口中2型糖尿病及其相关危险因素患病率的差异。对这两个人口群体的诊断标准[空腹血糖（FBG）和口服葡萄糖耐量试验（OGTT）]进行比较和回顾。
在一项横断面调查中，随机选取了1555名来自城市社区和4757名来自农村社区（年龄≥20岁）、具有相似文化和种族背景的受试者。测定了所有人的FBG值，并对选定数量的受试者（城市476名，农村1046名）在口服75克葡萄糖后测定了葡萄糖毛细血管血样2小时后的血糖值。
发现城市人口中糖尿病患病率（8.1%）高于农村人口（2.3%）。在对多个混杂变量进行校正后，年龄、性别和男性腰臀比是城市和农村受试者空腹及葡萄糖后2小时血糖值的显著危险因素。在城市（kappa 0.41）和农村（kappa 0.40）地区，FBG和OGTT之间的一致性都较差。
尽管体重指数（BMI）相似，但与农村受试者相比，城市人口中糖尿病（DM）的患病率更高。肥胖、腰臀比或高血压的差异无法解释城市人口中2型糖尿病发病率的上升。
