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[炎症过程的药理学研究。多形核中性粒细胞趋化性的改变]

[Pharmacologic study of inflammatory processes. Modification of polynuclear neutrophil chemotaxis].

作者信息

Giroud J P, Roch-Arveiller M, Bradshaw D

出版信息

C R Seances Soc Biol Fil. 1979;173(2):270-81.

PMID:159752
Abstract

A study of rat polymorphonuclear chemotaxis has been made by a direct microscopic method and the effect of inflammatory reactions induced by carrageenan, calcium pyrophosphate and complete Freund's adjuvant has been studied. In addition the action of various drugs such as cholera toxin, colchicine, prostaglandins and certain immunomodulators, was investigated. The results have been analysed with special regard to the role of chemotaxis in inflammatory responses.

摘要

通过直接显微镜检查法对大鼠多形核白细胞趋化性进行了研究,并研究了角叉菜胶、焦磷酸钙和完全弗氏佐剂诱导的炎症反应的影响。此外,还研究了霍乱毒素、秋水仙碱、前列腺素和某些免疫调节剂等各种药物的作用。已特别针对趋化性在炎症反应中的作用对结果进行了分析。

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