Mangold M C, Callen J P
Department of Medicine, University of Louisville, School of Medicine, KY.
J Am Acad Dermatol. 1992 Apr;26(4):579-84. doi: 10.1016/0190-9622(92)70084-s.
Cutaneous manifestations are common in Wegener's granulomatosis and may occur at any time during the illness.
Our purpose was to describe the relation of the appearance of cutaneous leukocytoclastic vasculitis to activity and other manifestations of Wegener's granulomatosis.
Three patients with Wegener's granulomatosis who had recent onset of skin lesions are reported. Data regarding the relation of their cutaneous disease to their systemic disease was collected.
In each case, onset of the skin lesions of biopsy-proven cutaneous leukocytoclastic vasculitis was associated with activation of the systemic features of Wegener's granulomatosis.
皮肤表现常见于韦格纳肉芽肿病，可在病程中的任何时候出现。
我们的目的是描述皮肤白细胞破碎性血管炎的出现与韦格纳肉芽肿病的活动及其他表现之间的关系。
报告了3例近期出现皮肤病变的韦格纳肉芽肿病患者。收集了有关其皮肤疾病与全身疾病关系的数据。
在每例患者中，经活检证实的皮肤白细胞破碎性血管炎的皮肤病变出现均与韦格纳肉芽肿病的全身症状激活有关。
