Iacono Pierluigi, Da Pozzo Stefano, Vattovani Odilla, Tognetto Daniele, Ravalico Giuseppe
Eye Clinic, University of Trieste, 34129 Trieste, Italy.
J Cataract Refract Surg. 2005 May;31(5):1042-9. doi: 10.1016/j.jcrs.2004.09.054.
To assess the effect of cataract phacoemulsification and intraocular lens (IOL) implantation on retinal nerve fiber layer (RNFL) thickness using scanning laser polarimetry (SLP).
Eye Clinic, Trieste University, Italy.
Forty-eight eyes were evaluated prospectively the day before and 30 days after cataract phacoemulsification and foldable IOL implantation. In each eye, lens opacity grading according to the Lens Opacities Classification System III (LOCS III), and axial length (AL) measurements were performed. Retinal nerve fiber layer thickness was quantified at baseline by means of SLP and anterior segment birefringence compensation was evaluated acquiring macular retardation map (MRM). Acrylic and silicone IOLs were implanted randomly. After surgery, RNFL thickness was reevaluated, and MRM was reacquired. Macular retardation map pattern variations regarding baseline profile were classified into 3 groups: no variation, bow-tie profile enhancement, or attenuation. Distribution of IOL power, AL, and cataract type in the 3 groups was assessed, as were presurgery and postsurgery SLP parameters with mean values (+/-SD) compared by paired t test.
Twenty-two eyes (Group 1, 45.8%) showed no MRM variation, 14 (Group 2, 29.2%) an enhancement, and 12 (Group 3, 25%) an attenuation. In Group 1, no significant RNFL thickness variation occurred. In Group 2, variation 10% to 15% was measured, whereas thickening a 8% to 15% thinning appeared in Group 3. Variations occurred irrespective of IOL material, AL, or cataract type.
Cataract surgery with IOL implantation was associated with an MRM profile change and RNFL thickness variations in 54.2% of eyes. Variations are probably related to opacified lens removal. A new baseline SLP reading is mandatory after cataract surgery.
使用扫描激光偏振仪（SLP）评估白内障超声乳化吸除联合人工晶状体（IOL）植入术对视网膜神经纤维层（RNFL）厚度的影响。
意大利的里雅斯特大学眼科诊所。
对48只眼睛在白内障超声乳化吸除联合可折叠IOL植入术前一天及术后30天进行前瞻性评估。对每只眼睛进行晶状体混浊程度分级（根据晶状体混浊分级系统III[LOCS III]）以及眼轴长度（AL）测量。通过SLP在基线时对视网膜神经纤维层厚度进行定量，并通过获取黄斑区延迟图（MRM）评估眼前节双折射补偿情况。随机植入丙烯酸酯和硅酮IOL。术后重新评估RNFL厚度并再次获取MRM。将黄斑区延迟图模式相对于基线轮廓的变化分为3组：无变化、领结轮廓增强或减弱。评估3组中IOL度数、AL和白内障类型的分布情况，以及术前和术后的SLP参数，采用配对t检验比较平均值（±标准差）。
22只眼睛（第1组，45.8%）显示MRM无变化，14只（第2组，29.2%）增强，12只（第3组，25%）减弱。第1组中，RNFL厚度无显著变化。第2组中，测量到变化为10%至15%，而第3组中出现了8%至15%的增厚或变薄。无论IOL材料、AL或白内障类型如何，均出现了变化。
白内障超声乳化吸除联合IOL植入术与54.2%的眼睛出现MRM轮廓改变和RNFL厚度变化有关。这些变化可能与混浊晶状体的摘除有关。白内障手术后必须进行新的基线SLP读数测量。
