Deane G B, Stokes M Dale
Marine Physical Laboratory, Scripps Institution of Oceanography, University of California at San Diego, La Jolla, CA 92093-0238, USA.
J Theor Biol. 2005 Nov 21;237(2):147-69. doi: 10.1016/j.jtbi.2005.04.002. Epub 2005 Jun 22.
A model is presented for the flash response of bioluminescent dinoflagellates stimulated by fluid shear. The model is based on the idea that the response of an individual cell to stimulation is inherently probabilistic, and can be modeled as a Poisson process over short time scales. A new cell parameter, the cell anxiety, is introduced to parameterize the probability of flashing. The statistical model is incorporated into a description of fully developed fluid flow in pipes and a cylindrical Couette chamber, and found to compare favorably with previously published data from experiments.
提出了一个关于流体剪切刺激下生物发光甲藻闪光响应的模型。该模型基于这样一种观点,即单个细胞对刺激的响应本质上是概率性的,并且在短时间尺度上可以建模为泊松过程。引入了一个新的细胞参数——细胞焦虑度,以参数化闪光的概率。该统计模型被纳入到对管道和圆柱形库埃特腔中充分发展的流体流动的描述中,并发现与先前发表的实验数据相比具有优势。