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从网纹原甲藻中分离并鉴定（44-R，S）-44,55-二羟基虾夷毒素及其在新西兰、挪威和加拿大贝类提取物中的存在情况。

Isolation and identification of (44-R,S)-44,55-dihydroxyyessotoxin from Protoceratium reticulatum, and its occurrence in extracts of shellfish from New Zealand, Norway and Canada.

作者信息

Finch Sarah C, Wilkins Alistair L, Hawkes Allan D, Jensen Dwayne J, MacKenzie A Lincoln, Beuzenberg Veronica, Quilliam Michael A, Olseng Christine D, Samdal Ingunn A, Aasen John, Selwood Andrew I, Cooney Janine M, Sandvik Morten, Miles Christopher O

机构信息

AgResearch Ltd, Ruakura Research Centre, Private Bag 3123, Hamilton, New Zealand.

出版信息

Toxicon. 2005 Aug;46(2):160-70. doi: 10.1016/j.toxicon.2005.03.007.

DOI:10.1016/j.toxicon.2005.03.007
PMID:15975615
Abstract

44,55-Dihydroxyyessotoxin (1) was isolated from extracts of Protoceratium reticulatum and identified by analysis of its one- and two-dimensional NMR and mass spectra. In addition, LC-MS methods revealed the presence of compounds tentatively identified as (44-R,S)-44,55-dihydroxy-41a-homoyessotoxin (2) and (44-R,S)-44,55-dihydroxy-9-methyl-41a-homoyessotoxin (3). LC-MS analyses indicate that 1 is a constituent of P. reticulatum in New Zealand and Norway, and it was present in three species of mussels from New Zealand, Norway, and Canada.

摘要

44,55-二羟基岩沙海葵毒素（1）从网纹原甲藻提取物中分离得到，并通过一维和二维核磁共振光谱以及质谱分析进行鉴定。此外，液相色谱-质谱联用方法揭示了初步鉴定为（44-R,S）-44,55-二羟基-41a-高岩沙海葵毒素（2）和（44-R,S）-44,55-二羟基-9-甲基-41a-高岩沙海葵毒素（3）的化合物的存在。液相色谱-质谱联用分析表明，1是新西兰和挪威网纹原甲藻的一种成分，并且存在于来自新西兰、挪威和加拿大的三种贻贝中。

相似文献

1
Isolation and identification of (44-R,S)-44,55-dihydroxyyessotoxin from Protoceratium reticulatum, and its occurrence in extracts of shellfish from New Zealand, Norway and Canada.从网纹原甲藻中分离并鉴定（44-R，S）-44,55-二羟基虾夷毒素及其在新西兰、挪威和加拿大贝类提取物中的存在情况。
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Mar Drugs. 2008 May 7;6(2):73-102. doi: 10.3390/md20080005.
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Azaspiracid shellfish poisoning: a review on the chemistry, ecology, and toxicology with an emphasis on human health impacts.azaspiracid贝类中毒：关于化学、生态和毒理学的综述，重点关注对人类健康的影响。
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The biosynthesis of polyketide metabolites by dinoflagellates.甲藻对聚酮化合物代谢产物的生物合成。
Adv Appl Microbiol. 2006;59:93-125. doi: 10.1016/S0065-2164(06)59004-5.