Nagel F, Foelster-Holst R
Klinik für Dermatologie, Allergologie und Venerologie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Brunswiker Strasse 10, 24105 Kiel.
Hautarzt. 2006 Feb;57(2):121-6. doi: 10.1007/s00105-005-0981-y.
Melkersson-Rosenthal syndrome is a rare disorder characterized by a triad of recurrent orofacial swelling, recurrent paralysis of the facial nerve and lingua plicata. The complete triad only occurs in 25% of MRS cases. Monosymptomatic or oligosymptomatic variants are more frequent; other findings include granulomas in other facial sites, regional lymphadenopathy, fever, psychotic disorders and hyperplastic gingivitis are associated with MRS. This can be a diagnostic challenge. The etiology and pathogenesis of MRS are unknown. Corticosteroids or clofazimine appear the best therapeutic options.
梅尔克森－罗森塔尔综合征是一种罕见疾病，其特征为复发性口面部肿胀、面神经反复麻痹和沟纹舌三联征。完整的三联征仅出现在25%的梅尔克森－罗森塔尔综合征病例中。单症状或少症状变体更为常见；其他表现包括面部其他部位的肉芽肿、局部淋巴结病、发热、精神障碍和增生性牙龈炎与梅尔克森－罗森塔尔综合征相关。这可能是一个诊断挑战。梅尔克森－罗森塔尔综合征的病因和发病机制尚不清楚。皮质类固醇或氯法齐明似乎是最佳治疗选择。
