Mahler V, Kiesewetter F
Dermatologische Universitätsklinik Erlangen.
HNO. 1996 Aug;44(8):471-5.
Atypical forms of Melkersson-Rosenthal syndrome are difficult to diagnose, especially when occurring in uncommon facial locations. The clinical and histological characteristics of these forms are illustrated in a typical case. We report our experiences with a 59-year-old white male who had increasing swelling of his tongue for years and a recent onset of perioral swelling. A plicated tongue was present, while symptoms of facial and trigeminal nerve involvement were absent. Minor symptoms present were speech impediments, dysgeusia, episodes of hypersalivation and burning sensations on eating. Biopsies revealed sarcoid and lymphonodular-plasmocytic granulomatous infiltrates. These findings were consistent with a diagnosis of an oligosymptomatic Melkersson-Rosenthal syndrome. Swelling of the tongue and that of the perioral region was controlled with clofazimine therapy.
非典型形式的梅尔克森 - 罗森塔尔综合征难以诊断，尤其是当它出现在不常见的面部位置时。这些形式的临床和组织学特征在一个典型病例中得到了说明。我们报告了一位59岁白人男性的病例，他多年来舌头肿胀不断加重，近期出现口周肿胀。存在皱襞舌，同时无面部和三叉神经受累症状。存在的轻微症状有言语障碍、味觉障碍、唾液分泌过多发作以及进食时的烧灼感。活检显示有结节病和淋巴结节 - 浆细胞性肉芽肿浸润。这些发现符合少症状性梅尔克森 - 罗森塔尔综合征的诊断。用氯法齐明治疗控制了舌头和口周区域的肿胀。
