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[Developing and testing a method of in silico identification and characterization of meiotic DNA].

作者信息

Grishaeva T M, Dadashev S Ia, Bogdanov Iu F

出版信息

Genetika. 2005 May;41(5):697-701.

PMID:15977823
Abstract

A method of in silico search for specific repetitive DNA sequences related to the synaptonemal complex (meiDNA) in mammalian genomes was developed. A study of the distribution of these repeats over chromosomes revealed their scarcity on the Y chromosome and a decrease in recombination frequency in regions enriched in meiDNA. The results are discussed in context of the model of the looplike meiotic chromosome organization during the formation of the synaptonemal complex.

摘要

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