Lachapelle K, Graham A M, Symes J F
Department of Surgery, Royal Victoria Hospital, McGill University, Montreal, Canada.
J Vasc Surg. 1992 Jun;15(6):964-70; discussion 970-1.
A cost-effective method to reduce mortality rates after abdominal aortic aneurysm repair centers on selecting and investigating only those patients at risk for cardiac-related death. All 146 patients undergoing asymptomatic abdominal aortic aneurysm repair over a 5-year period (1986 to 1990) were retrospectively placed into one of the three following groups on the basis of a clinical evaluation. Group I: no history of myocardial infarction or angina, no congestive heart failure, and no ischemic changes on electrocardiogram (ECG). Group II: history of myocardial infarction or class I-II angina or ischemic changes on ECG. Group III: presence of congestive heart failure or class III-IV angina. Patients in group I had no further cardiac work-up; patients in group II with angina had left ventricular ejection fraction assessment by multiple gated acquisition (all greater than 37%) and were cleared for operation by a cardiologist; patients in group II without angina had no further cardiac work-up; patients in group III had coronary angiography and then coronary revascularization. The overall mortality rate was 4.8%, with a cardiac mortality rate of 3.4%. The mortality rate in group I (n = 64) was 1.8%, with no cardiac-related deaths; the mortality rate in group II (n = 63) was 9.5% (8% cardiac-related deaths). No deaths occurred in group III (n = 19). The difference between the cardiac mortality rates in groups I and II was significant (p = 0.02) as was the postoperative cardiac morbidity: total myocardial infarctions (p less than 0.001); congestive heart failure (p = 0.02); tachyarrhythmias (p = 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)
一种降低腹主动脉瘤修复术后死亡率的经济有效方法,主要围绕仅筛选和检查那些有心脏相关死亡风险的患者。对1986年至1990年这5年期间接受无症状腹主动脉瘤修复的146例患者,根据临床评估进行回顾性分组。第一组:无心肌梗死或心绞痛病史,无充血性心力衰竭,心电图(ECG)无缺血性改变。第二组:有心肌梗死病史或Ⅰ - Ⅱ级心绞痛或ECG有缺血性改变。第三组:有充血性心力衰竭或Ⅲ - Ⅳ级心绞痛。第一组患者无需进一步心脏检查;第二组有心绞痛的患者通过多门控采集评估左心室射血分数(均大于37%),并由心脏病专家批准手术;第二组无心绞痛的患者无需进一步心脏检查;第三组患者进行冠状动脉造影,然后进行冠状动脉血运重建。总体死亡率为4.8%,心脏死亡率为3.4%。第一组(n = 64)的死亡率为1.8%,无心脏相关死亡;第二组(n = 63)的死亡率为9.5%(8%为心脏相关死亡)。第三组(n = 19)无死亡。第一组和第二组的心脏死亡率差异显著(p = 0.02),术后心脏发病率差异也显著:总心肌梗死(p < 0.001);充血性心力衰竭(p = 0.02);快速心律失常(p = 0.05)。(摘要截断于250字)