Hollier L H, Reigel M M, Kazmier F J, Pairolero P C, Cherry K J, Hallett J W
J Vasc Surg. 1986 May;3(5):712-7.
Recent reports in the literature have promulgated nonresective treatment of abdominal aortic aneurysm as a safer procedure than conventional aneurysmectomy with graft replacement in high-risk patients. This review of 106 high-risk patients who underwent conventional aneurysm repair between 1980 and 1985 was undertaken to compare the relative risks, perioperative morbidity, and operative mortality of these patients to that reported for patients treated by nonresective therapy. Excluded were those patients who had rupture initially or underwent a concomitant renovascular procedure. Patients were considered to be at high risk if they met one or more of the following criteria: age equal to or greater than 85 years; receiving oxygen at home, PO2 less than 50 torr, or forced midexpiratory flow less than 25% of predicted; serum creatinine equal to or greater than 3 mg/dl; biopsy-proven cirrhosis with ascites; retroperitoneal fibrosis; or New York Heart Association functional class III-IV angina, left ventricular ejection fraction less than 30%, recent congestive heart failure, complex ventricular ectopy, large left ventricular aneurysm, severe valvular disease, recurrent congestive heart failure or angina after coronary artery bypass grafting, or severe unreconstructed coronary artery disease confirmed by angiography. The mortality rate for conventional aneurysm repair in high-risk patients was 5.7%, compared with a reported 7% mortality rate for nonresective therapy. In those patients with severe cardiac dysfunction, intraoperative pharmacologic manipulation and the selective use of intra-aortic balloon counterpulsation appeared helpful in achieving survival.(ABSTRACT TRUNCATED AT 250 WORDS)
近期文献报道称,对于高危患者,腹主动脉瘤的非切除治疗比传统的动脉瘤切除术加移植物置换术更安全。本研究回顾了1980年至1985年间接受传统动脉瘤修复术的106例高危患者,以比较这些患者与接受非切除治疗患者的相对风险、围手术期发病率和手术死亡率。最初有破裂或同时接受肾血管手术的患者被排除在外。如果患者符合以下一项或多项标准,则被认为是高危患者:年龄等于或大于85岁;在家吸氧、动脉血氧分压小于50托或用力呼气中期流速小于预测值的25%;血清肌酐等于或大于3毫克/分升;活检证实为肝硬化伴腹水;腹膜后纤维化;或纽约心脏协会心功能III-IV级心绞痛、左心室射血分数小于30%、近期充血性心力衰竭、复杂室性早搏、大的左心室动脉瘤、严重瓣膜病、冠状动脉搭桥术后复发性充血性心力衰竭或心绞痛,或经血管造影证实的严重未重建冠状动脉疾病。高危患者传统动脉瘤修复术的死亡率为5.7%,而非切除治疗报告的死亡率为7%。在那些有严重心脏功能障碍的患者中,术中药物处理和选择性使用主动脉内球囊反搏似乎有助于提高生存率。(摘要截短至250字)