Rossi Lauren L, Basu Amit
Department of Chemistry, Brown University, Providence, RI 02912, USA.
Bioorg Med Chem Lett. 2005 Aug 1;15(15):3596-9. doi: 10.1016/j.bmcl.2005.05.081.
1-Glycosyl-4-phenyl triazoles have been prepared via a copper-mediated [3+2] cycloaddition of glycosyl azides with phenylacetylene. These triazoles have been evaluated for their ability to inhibit the enzymatic activity of glycosidases.
1-糖基-4-苯基三唑是通过铜介导的糖基叠氮化物与苯乙炔的[3+2]环加成反应制备的。已对这些三唑抑制糖苷酶酶活性的能力进行了评估。
