Vlahovicek Kristian, Pintar Alessandro, Parthasarathi Laavanya, Carugo Oliviero, Pongor Sándor
Protein Structure and Bioinformatics Group, International Centre for Genetic Engineering and Biotechnology, Area Science Park, 34012 Trieste, Italy.
Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W252-4. doi: 10.1093/nar/gki362.
The WWW servers at http://www.icgeb.org/protein/ are dedicated to the analysis of protein 3D structures submitted by the users as the Protein Data Bank (PDB) files. CX computes an atomic protrusion index that makes it possible to highlight the protruding atoms within a protein 3D structure. DPX calculates a depth index for the buried atoms and makes it possible to analyze the distribution of buried residues. CX and DPX return PDB files containing the calculated indices that can then be visualized using standard programs, such as Swiss-PDBviewer and Rasmol. PRIDE compares 3D structures using a fast algorithm based on the distribution of inter-atomic distances. The options include pairwise as well as multiple comparisons, and fold recognition based on searching the CATH fold database.
位于http://www.icgeb.org/protein/ 的万维网服务器致力于分析用户以蛋白质数据库（PDB）文件形式提交的蛋白质三维结构。CX计算原子突出指数，从而能够突出显示蛋白质三维结构中的突出原子。DPX计算埋藏原子的深度指数，并能够分析埋藏残基的分布。CX和DPX返回包含计算指数的PDB文件，然后可以使用诸如Swiss-PDBviewer和Rasmol等标准程序进行可视化。PRIDE使用基于原子间距离分布的快速算法比较三维结构。选项包括成对比较以及多重比较，以及基于搜索CATH折叠数据库的折叠识别。
