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估算撒哈拉以南非洲地区因艾滋病及其他原因导致的孤儿数量的方法。

Methods to estimate the number of orphans as a result of AIDS and other causes in Sub-Saharan Africa.

作者信息

Grassly Nicholas C, Timaeus Ian M

机构信息

Department of Infectious Disease Epidemiology, Imperial College Faculty of Medicine, St. Mary's Campus, London, United Kingdom.

出版信息

J Acquir Immune Defic Syndr. 2005 Jul 1;39(3):365-75. doi: 10.1097/01.qai.0000156393.80809.fd.

Abstract

OBJECTIVE

To derive methods to estimate and project the fraction of children orphaned by AIDS and other causes.

METHODS

HIV/AIDS affects orphan numbers through increased adult and child mortality and reduced fertility of HIV-positive women. We extend an epidemiologic and demographic model used previously to estimate maternal orphans to paternal orphans. We account for the impact of HIV/AIDS on child survival by modeling the HIV status of the partners of men who die of AIDS or other causes based on data on the concordance of heterosexual partners. Subsequently, the proportion of orphans whose parents have both died is predicted by a regression model fitted to orphanhood data from 34 national demographic and health surveys (DHSs). The approach is illustrated with an application to Tanzania and compared with DHS estimates for the years 1992 and 1999.

RESULTS

Projections of the number and age distribution of orphans using these methods agree with survey data for Tanzania. They show the rise in orphanhood over the last decade that has resulted from the HIV epidemic.

CONCLUSIONS

The methods allow estimation of the numbers of children whose mother, father, or both parents have died for countries with generalized heterosexual HIV epidemics. These methods have been used to produce orphan estimates for high-prevalence countries published by Joint United Nations Program on HIV/AIDS, World Health Organization, United Nations Children's Fund, and US Agency for International Development in 2002 and 2004.

摘要

目的

推导估计和预测因艾滋病及其他原因成为孤儿的儿童比例的方法。

方法

艾滋病毒/艾滋病通过增加成人和儿童死亡率以及降低艾滋病毒呈阳性妇女的生育率来影响孤儿数量。我们扩展了先前用于估计母亲去世导致的孤儿数量的流行病学和人口统计学模型,以涵盖父亲去世导致的孤儿数量。我们根据异性伴侣一致性数据,对死于艾滋病或其他原因的男性伴侣的艾滋病毒感染状况进行建模,从而考虑艾滋病毒/艾滋病对儿童生存的影响。随后,通过对来自34项国家人口与健康调查(DHS)的孤儿数据拟合回归模型,预测父母双亡的孤儿比例。以坦桑尼亚为例说明了该方法,并与1992年和1999年的DHS估计值进行了比较。

结果

使用这些方法对孤儿数量和年龄分布的预测与坦桑尼亚的调查数据一致。这些预测显示了过去十年中因艾滋病毒流行导致的孤儿数量的增加。

结论

这些方法能够估计在异性传播艾滋病毒普遍流行的国家中,母亲、父亲或父母双亡的儿童数量。这些方法已被用于生成由联合国艾滋病毒/艾滋病联合规划署、世界卫生组织、联合国儿童基金会和美国国际开发署在2002年和2004年发布的高流行率国家的孤儿估计数。

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