Legardinier Sébastien, Cahoreau Claire, Klett Danièle, Combarnous Yves
Unité de Physiologie de la Reproduction et des Comportements, Institut National de la Recherche Agronomique (INRA), Centre National de la Recherche Scientifique (CNRS) et Université François Rabelais de Tours, 37 380 Nouzilly, France.
Reprod Nutr Dev. 2005 May-Jun;45(3):255-9. doi: 10.1051/rnd:2005018.
Natural eCG consists of as much as 45% carbohydrate side chains. The present paper deals with the analysis of the roles of the N- and O-linked saccharides of this hormone in the different steps of its activity and its possible replacement by recombinant eCG expressed in baculovirus-insect cell systems.
天然马绒毛膜促性腺激素(eCG)含有多达45%的碳水化合物侧链。本文探讨了该激素的N-连接和O-连接糖类在其活性不同阶段所起的作用,以及在杆状病毒-昆虫细胞系统中表达的重组eCG对其的可能替代作用。