Sellheyer Klaus, Krahl Dieter
Department of Dermatology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
Int J Dermatol. 2005 Jul;44(7):535-40. doi: 10.1111/j.1365-4632.2004.02536.x.
The term "hidradenitis suppurativa" is firmly entrenched in the dermatological literature although it refers to a false pathogenetic concept. The term was historically coined based merely on the characteristic distribution of the apocrine glands and the anatomical coincidence with the disease process. At center stage is not a suppurative inflammation of the apocrine sweat glands but an occlusion of the hair follicles, comparable to acne vulgaris. Reviewing the literature on this subject, we were astonished to find that even articles that concluded that the entity represents a form of follicular occlusion still referred to it as hidradenitis suppurativa. The disorder shares histopathological and clinical aspects with acne vulgaris modified under the special circumstances of anatomical regions rich in apocrine glands. It is acne inversa because, in contrast to acne vulgaris, the disease involves intertriginous localizations and not the regions classically affected by acne. We suggest that the term "hidradenitis suppurativa" for this disease should (finally) be abandoned in favour of "acne inversa".
“化脓性汗腺炎”这一术语在皮肤病学文献中已根深蒂固，尽管它指的是一个错误的发病机制概念。该术语在历史上仅是基于顶泌汗腺的特征性分布以及与疾病过程的解剖学巧合而创造的。处于核心地位的并非顶泌汗腺的化脓性炎症，而是毛囊阻塞，这与寻常痤疮类似。回顾关于这个主题的文献，我们惊讶地发现，即使是那些得出该疾病代表一种毛囊阻塞形式结论的文章，仍将其称为化脓性汗腺炎。这种疾病在富含顶泌汗腺的解剖区域的特殊情况下，与寻常痤疮有共同的组织病理学和临床特征。它是反向痤疮，因为与寻常痤疮不同，该疾病累及褶皱部位，而非寻常痤疮经典累及的区域。我们建议，对于这种疾病，“化脓性汗腺炎”这一术语（最终）应被摒弃，而采用“反向痤疮”。
