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人类尾部脂肪瘤中的畸胎瘤。

Teratoma in human tail lipoma.

作者信息

Park Se-Hyuck, Huh Jee Soon, Cho Ki Hong, Shin Yong Sam, Kim Se Hyck, Ahn Young Hwan, Cho Kyung Gi, Yoon Soo Han

机构信息

Department of Neurosurgery, Kandong Sacred Heart Hospital, Hallym University, Seoul, Korea.

出版信息

Pediatr Neurosurg. 2005 May-Jun;41(3):158-61. doi: 10.1159/000085876.

Abstract

We report a case of a rare congenital teratoma that developed in a lipoma attached to a remnant human tail. A male newborn baby presented with a large, 3-cm mass with an open margin, which pedunculated from a tail attached to the midline skin of the coccygeal area. Magnetic resonance images demonstrated multiple sacral spinal bifida without cord tethering, and also showed neural roots and a lipoma and teratoma with peripheral homogeneous high density and internal low density on T(2)-weighted images. Intraoperatively, we found and dissected two nerve roots from the filum terminale which extended into the mass. Pathologic examination of the mass revealed abnormal differentiation of respiratory epithelium and squamous cell metaplasia along the open margin of the mass, and mainly lipoma in the rest of the mass. We suggest that this case could support the hypothesis of transient teratomatous cells in the pathogenesis of the spina bifida with lumbosacral lipoma.

摘要

我们报告一例罕见的先天性畸胎瘤,其发生于附着于人类残余尾巴的脂肪瘤内。一名男性新生儿出现一个 3 厘米大、边缘开放的肿块,该肿块由附着于尾骨区域中线皮肤的尾巴带蒂长出。磁共振成像显示多发骶部脊柱裂但无脊髓栓系,并且在 T2 加权图像上还显示神经根以及一个脂肪瘤和畸胎瘤,其周边为均匀的高密度,内部为低密度。术中,我们从终丝中发现并分离出两条延伸至肿块内的神经根。对肿块的病理检查显示,沿着肿块开放边缘有呼吸上皮的异常分化和鳞状上皮化生,肿块其余部分主要为脂肪瘤。我们认为该病例可支持关于腰骶部脂肪瘤型脊柱裂发病机制中存在短暂性畸胎瘤细胞的假说。

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