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同一供体的两枚肾移植早期失功:摇头丸的作用?

Early loss of two renal grafts obtained from the same donor: role of ecstasy?

作者信息

Hurault de Ligny Bruno, El Haggan Wael, Comoz François, Lobbedez Thierry, Pujo Myriam, Griveau Anne Marie, Bottet Philippe, Bensadoun Henri, Ryckelynck Jean Philippe

机构信息

Department of Nephrology and Renal Transplantation, Caen University Hospital, Caen, France.

出版信息

Transplantation. 2005 Jul 15;80(1):153-6. doi: 10.1097/01.tp.0000158713.70266.06.

DOI:10.1097/01.tp.0000158713.70266.06
PMID:16003249
Abstract

Early loss of renal grafts is generally caused by vascular or immunologic complications. We describe two patients who received a kidney transplant from the same donor and lost their grafts during the first posttransplant week. Both cases presented necrotizing graft vasculopathy without inflammatory element. The donor was a 21-year-old woman who regularly used "ecstasy" over a 2-year period. After an extensive work-up to investigate the potential causes of graft loss, we considered the possibility of ecstasy being the cause of these two renal-graft losses.

摘要

肾移植早期丢失通常由血管或免疫并发症引起。我们描述了两名接受来自同一供体肾脏移植的患者,他们在移植后的第一周内失去了移植肾。两例均表现为无炎症成分的坏死性移植肾血管病。供体是一名21岁女性,在两年时间里经常使用摇头丸。在进行了广泛的检查以探究移植肾丢失的潜在原因后,我们认为摇头丸有可能是这两例肾移植丢失的原因。

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