Stîngu Cătilina Suzana, Turcu Tatiana, Dimitriu St
Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi, Facultatea de Medicină Dentară, Disciplina de Microbiologie.
Rev Med Chir Soc Med Nat Iasi. 2004 Oct-Dec;108(4):909-12.
Microbiological findings together with clinical and radiological diagnosis are essential for rationale use of antibiotics in periodontal disease. Methods used for microbiological diagnosis are: microscopy, cultivation, gas liquid chromatography, PCR, immuno-assays (ELISA, immunofluorescence), FISH. Each of them has some advantages and disadvantages related to cost, accessibility, sensitivity, duration. The most used today are cultivation and PCR techniques.
微生物学检查结果以及临床和影像学诊断对于牙周病抗生素的合理使用至关重要。用于微生物学诊断的方法有：显微镜检查、培养、气液色谱法、聚合酶链反应（PCR）、免疫测定法（酶联免疫吸附测定、免疫荧光）、荧光原位杂交技术（FISH）。它们每一种在成本、可及性、敏感性、检测时长方面都有一些优缺点。目前使用最多的是培养技术和聚合酶链反应技术。
