染色体分离：眼见为实。

Chromosome segregation: seeing is believing.

作者信息

Bloom Kerry

机构信息

Department of Biology, University of North Carolina at Chapel Hill, 27599-3280, USA.

出版信息

Curr Biol. 2005 Jul 12;15(13):R500-3. doi: 10.1016/j.cub.2005.06.033.

DOI:10.1016/j.cub.2005.06.033

PMID:16005281

Abstract

For chromosome segregation in mitosis, each centromere directs assembly of a complex, proteinaceous structure - the kinetochore, which connects the chromosome to microtubules of the mitotic spindle. A recent study has provided important new insights into the mechanism by which kinetochores capture spindle microtubules.

摘要

在有丝分裂过程中，为了实现染色体分离，每个着丝粒会引导一种复杂的蛋白质结构——动粒的组装，动粒将染色体与有丝分裂纺锤体的微管相连。最近的一项研究为动粒捕获纺锤体微管的机制提供了重要的新见解。