Hilakivi-Clarke L A, Lister R G
Laboratory of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland 20892.
J Comp Psychol. 1992 Jun;106(2):184-9. doi: 10.1037/0735-7036.106.2.184.
The behavior of isolated Cr:NIH(S) mice (Mus musculus) was studied in a holeboard test of exploration, in a plus-maze test of anxiety, in the resident-intruder paradigm of aggression, and in the swim test. Thereafter, mice that were matched for body weight were housed together in groups of 4-5. Within a week, 1 mouse per cage (the alpha) had attacked all its subordinate cagemates but lacked any signs of attack itself. Subordinate mice had bite marks on their tails and backs. When mice were isolated, no differences were found between the behavior of those that later became alphas and those that became subordinates. In contrast, after the establishment of the social hierarchy, alpha mice spent less time immobile in the swim test and had higher locomotor activities than did the subordinate mice. The results suggest that the differences in behavior between the alpha and subordinate mice result from aggressive social interactions in the home cage.
在探索性的洞板试验、焦虑的十字迷宫试验、侵略性的群居者-入侵者范式以及游泳试验中，对单独饲养的Cr:NIH(S)小鼠（小家鼠）的行为进行了研究。此后，将体重匹配的小鼠以4 - 5只为一组共同饲养。在一周内，每个笼子里有1只小鼠（占主导地位的小鼠）攻击了所有地位较低的同笼伙伴，但自身没有任何被攻击的迹象。地位较低的小鼠尾巴和背部有咬痕。当小鼠单独饲养时，后来成为占主导地位的小鼠和成为从属地位的小鼠在行为上没有差异。相比之下，在社会等级制度建立后，占主导地位的小鼠在游泳试验中静止不动的时间较少，并且比从属地位的小鼠具有更高的运动活性。结果表明，占主导地位的小鼠和从属地位的小鼠在行为上的差异是由笼内具有攻击性的社会互动导致的。
