Todd D J, Handley J, Walsh M, Dolan O, Burrows D
Department of Dermatology, Royal Victoria Hospital, Belfast, UK.
Contact Dermatitis. 1992 Jan;26(1):22-6. doi: 10.1111/j.1600-0536.1992.tb00863.x.
The keratinocyte expression of class II MHC antigens HLA-DR, DP and DQ was studied in 20 long-lasting allergic patch test reactions and 17 normal allergic patch tests reactions. No significant difference in the expression of these antigens in the 2 groups was detected. No 1 allergen was responsible for the majority of long-lasting allergic patch test reactions. The immunological mechanisms which may contribute to long-lasting allergic patch test reactions are discussed with reference to HLA-DR keratinocytes.
