Khairallah S H, Byrne K A, Tabbara K F
Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Doc Ophthalmol. 1992;79(3):269-76. doi: 10.1007/BF00158257.
We studied a total of 27 cases of fungal keratitis is Saudi Arabia. History of trauma was found in 9 patients, and previous use of topical steroids in 6 patients. In the majority of patients the onset of the disease was in fall and spring. The most frequent cause of fungal keratitis was found to be Aspergillus spp., and these were isolated from 11 cases (41%). Eight of the 11 isolates were Aspergillus flavus. Other causes of keratomycosis included: Fusarium, Candida, and Mycelia sterilia. All patients were treated with antifungal therapy and 18 patients required surgical intervention. Vision improved among 11 patients, remained the same in 4 patients, and deteriorated after treatment in 6 patients. (6 patients failed to return for follow-up.) Four of the 27 patients developed fungal endophthalmitis. The high prevalence of Aspergillus spp. may be due to the fact that spores of Aspergillus can survive the hot and dry weather of Saudi Arabia.
我们在沙特阿拉伯共研究了27例真菌性角膜炎患者。9例患者有外伤史，6例患者曾使用过局部类固醇。大多数患者的疾病发作发生在秋季和春季。发现真菌性角膜炎最常见的病因是曲霉菌属，从11例（41%）患者中分离出该菌。11株分离菌中有8株是黄曲霉。角膜真菌病的其他病因包括：镰刀菌、念珠菌和无菌丝菌。所有患者均接受了抗真菌治疗，18例患者需要手术干预。11例患者视力改善，4例患者视力不变，6例患者治疗后视力恶化。（6例患者未返回进行随访。）27例患者中有4例发生真菌性眼内炎。曲霉菌属的高患病率可能是由于曲霉菌的孢子能够在沙特阿拉伯炎热干燥的天气中存活。
