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估算1997 - 1998年哥本哈根市问题阿片类药物使用的流行率。

Estimating the prevalence of problem opioid use in Copenhagen 1997-1998.

作者信息

Ishøy Torben, Haastrup Lene, Hay Gordon

机构信息

Department of Social Medicine, DK-2600 Glostrup.

出版信息

Dan Med Bull. 2004 Feb;51(1):114-6.

Abstract

INTRODUCTION

Estimates of the prevalence of drug use in Denmark were, until 1999, based on the mortality multiplier method. This paper presents a study estimating the prevalence of problem opioid use in the Greater Copenhagen region using the capture-recapture method.

METHODS AND MATERIAL

Records from the prehospital mobile emergency care unit, The Copenhagen Prehospital Research Database, were searched with a particular focus on treatment of opioid overdose. In addition, data from The National Register of Drug Users in Treatment in Greater Copenhagen were analysed for the years 1997 and 1998. Four samples were used within the capture-recapture analysis, ie the Prehospital Research Database for 1997/1998 and the Register of Drug Users in Treatment for the same period.

RESULTS

The estimates from the stratified capture-recapture analyses, when summed up, suggest that there is a hidden population of 4116 and thus a total population of 6992 opioid users in Greater Copenhagen (population approx 700,000). This corresponds to a rate of 10 per 1000 inhabitants aged 15-54 years. The 95% confidence attached to this estimate is 5787 to 10,885.

DISCUSSION

The prevalence rate of 10 per 1000 inhabitants aged 15-54 years is comparable to figures found in similar cities in Europe. A previous study of Central Copenhagen calculated the rate to be 12.4 per 1000 inhabitants between 15 and 59 years. It seems reasonable that the estimate of prevalence of problem drug use in Greater Copenhagen is lower than the prevalence in Central Copenhagen, as the city area is more urbanised and has a slightly different demographic and socio-economic profile. About 75% of all opioid overdose incidents are assumed to occur in the central district of the city during the observed period.

摘要

引言

直到1999年,丹麦药物使用流行率的估计是基于死亡率乘数法。本文介绍了一项使用捕获再捕获法估计大哥本哈根地区问题阿片类药物使用流行率的研究。

方法与材料

检索了院前移动急救单位(哥本哈根院前研究数据库)的记录,特别关注阿片类药物过量治疗情况。此外,还分析了1997年和1998年大哥本哈根地区国家药物使用者治疗登记处的数据。在捕获再捕获分析中使用了四个样本,即1997/1998年的院前研究数据库和同期的药物使用者治疗登记处。

结果

分层捕获再捕获分析的估计值汇总后表明,大哥本哈根地区(人口约70万)存在4116人的隐藏人群,因此阿片类药物使用者总数为6992人。这相当于每1000名15至54岁居民中有10人使用阿片类药物。该估计值的95%置信区间为5787至10885。

讨论

每1000名15至54岁居民中有10人的流行率与欧洲类似城市的数字相当。此前对哥本哈根市中心的一项研究计算出,15至59岁居民中每1000人中有12.4人使用阿片类药物。大哥本哈根地区问题药物使用流行率的估计低于哥本哈根市中心,这似乎是合理的,因为城市地区更加城市化,人口统计学和社会经济概况略有不同。在观察期内,所有阿片类药物过量事件中约75%被认为发生在市中心区。

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